The benefits of nature-based systems in a and uncertain world

Multifunctional nature-based solutions (NBS) can help urban areas become more climate proof and adaptable and provide a range of societal goals. Alongside chronic impacts from climate change, the Covid-19 pandemic has illustrated the disruption that unexpected and acute shocks can bring to society. Measures such as NBS can help reduce the vulnerability of urban areas and increase resilience. Traditional infrastructure planning relies on strong business cases to demonstrate the economic value of a scheme. Numerous approaches assign economic value to the benefits from using NBS. However, this value is more than what can be accounted for by traditional finance methods, as there are many different perspectives on 'value'. Decision making processes for selection of NBS measures require stronger integration of these value perspectives. This paper considers these perspectives in the business models that are being used in the decision processes regarding use and selection of NBS. Examples are drawn from case studies in the EU Begin project and also from the Living with Water partnership in the UK, which illustrate how value perspectives can be included in business cases for NBS, also signposting the need to account for potential future changes using scenario planning.

The benefits of nature-based systems in a changing and uncertain world

Multifunctional nature-based solutions (NBS) can help urban areas become more climate proof and adaptable and provide a range of societal goals. Alongside chronic impacts from climate change, the Covid-19 pandemic has illustrated the disruption that unexpected and acute shocks can bring to society. Measures such as NBS can help reduce the vulnerability of urban areas and increase resilience. Traditional infrastructure planning relies on strong business cases to demonstrate the economic value of a scheme. Numerous approaches assign economic value to the benefits from using NBS. However, this value is more than what can be accounted for by traditional finance methods, as there are many different perspectives on 'value'. Decision making processes for selection of NBS measures require stronger integration of these value perspectives. This paper considers these perspectives in the business models that are being used in the decision processes regarding use and selection of NBS. Examples are drawn from case studies in the EU Begin project and also from the Living with Water partnership in the UK, which illustrate how value perspectives can be included in business cases for NBS, also signposting the need to account for potential future changes using scenario planning. [ FROM AUTHOR] Copyright of Proceedings of the Institution of Civil Engineers: Engineering Sustainability is the property of Thomas Telford Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

In-silico INVESTIGATION OF FERULIC ACID DERIVATES AGAINST MAIN PROTEASE SARS-COV

Ferulic acid is one of the natural compounds which is prevalent in various plants. This compound has known to possess extensive biological activity to get good health and well-being. In this study, we designed 23 derivates of ferulic acid and evaluate their potency in silico as potential SARS-CoV Mpro inhibitors. Furthermore, in silico ADME profiles of designed compounds were evaluated to verify whether the ferulic acid analogs possess an acceptable pharmacokinetic profile. The molecular docking result using AutoDock 4.2.6 showed that compound FA-24, which contained dihydro benzoxazine moiety, possesses a better docking score among the designed compound. Five top compounds based on docking score (FA-16, FA-17, FA-18, FA-23, and FA-24) were then evaluated using molecular dynamics for 10 ns, followed by free binding energy evaluation using the MM-PBSA approach. The result indicated that all compounds formed stable complexes with the enzyme for 100 ns. However, MM-PBSA result showed that compound FA-16, which contained phenyl benzoate moiety, possess higher free binding energy. It is argued that this difference was due to the nature of free binding energy evaluation, which was based on molecular dynamics results. Although, both the docking score and free binding energy of the designed compound are lower than the native ligand (AZP), it is believed that further structure modification could be performed to address this shortcoming. Ultimately, all designed ferulic acid analogs possess optimal absorption and drug-likeness characteristic, while several compounds were predicted to interact with isoforms of CYP450. © 2022, Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma. All rights reserved.

Chemoinformatics approach to design and develop vanillin analogs as COX-1 inhibitor

Background: Coronary Heart Disease (CHD), commonly known as the silent killer, impacted the severity of COVID-19 patients during the pandemic era. Thrombosis or blood clots create the buildup of plaque on the coronary artery walls of the heart, which leads to coronary heart disease. Cyclooxygenase 1 (COX-1) is involved in the production of prostacyclin by systemic arteries;hence, inhibiting the COX-1 enzyme can prevent platelet reactivity mediated by prostacyclin. To obtain good health and well-being, the research of discovery of new drugs for anti-thrombotic still continue. Objective(s): This study aims to predict the potential of 17 compounds owned by the vanillin analog to COX-1 receptor using in silico. Method(s): This research employed a molecular docking analysis using Toshiba hardware and AutoDock Tools version 1.5.7, ChemDraw Professional 16.0, Discovery Studio, UCSF Chimera software, SWISSADME and pKCSM, a native ligand from COX-1 (PDB ID: 1CQE) was validated. Result(s): The validation result indicated that the RMSD was <2 A. The 4-formyl-2-methoxyphenyl benzoate compound had the lowest binding energy in COX-1 inhibition with a value of-7.70 A. All vanillin derivatives show good intestinal absorption, and the predicted toxicity indicated that they were non-hepatotoxic. All these compounds have the potential to be effective antithrombotic treatments when consumed orally. Conclusion(s): In comparison to other vanillin derivative com-pounds, 4-formyl-2-methoxyphenyl benzoate has the lowest binding energy value;hence, this analog can continue to be synthesized and its potential as an antithrombotic agent might be confirmed by in vivo studies.Copyright © the Author(s), 2023.

Cultivating resilience among Hong Kong's underprivileged ethnic minority groups in the face of a pandemic through a social justice lens

Purpose: In this study, the authors investigated ways to cultivate resilience through a social justice lens among ethnic minorities against COVID-19 in Hong Kong. Design/methodology/approach: A qualitative (case study) methodology was adopted to interview 15 social service providers from diverse ethnic backgrounds serving disadvantaged ethnic minority groups (South and Southeast Asian groups from low-income households, foreign domestic workers and asylum seekers/refugees). Findings: Two major protective factors were identified, contributing to the development of resilience among diverse ethnic groups: (1) individual-based resilience (including being optimistic) and (2) socio-environmental factors (including ongoing support from strong family, peer and religious settings' support, consulates' support, on-going material and nonmaterial donations, support of young volunteers and importance of online connection and communication) using the integration of resilience and social justice frameworks. Originality/value: This study showed that the protective factors were found to dynamically interact with each other and the environment. The present study recommends additional culturally sensitive service and policy implications for preventing the long-term impact of mass crises among Hong Kong's marginalized minorities. © 2023, Emerald Publishing Limited.

Delivering a new helicopter base at Kai Tak for the Hong Kong Government Flying Service

An additional helicopter base has been built for the Government Flying Service at the former Kai Tak airport runway site in Hong Kong, China. The base allows high-rise development to take place at Tung Chung new town near the service's existing base at Hong Kong International airport, which would have restricted emergency helicopter operations during poor weather. The project involved construction of a take-off and landing pad, parking bays and hangar for two helicopters, plus an office building for the flight planning centre and air command and control centre. This paper describes how use of an NEC contract helped ensure close collaboration between the employer and contractor, leading to timely completion with zero accidents despite restrictions caused by the Covid-19 pandemic.

Toward a sustained recovery of the lodging sector: a management path to lessen the Corona Variants upshots

The lodging industry is an important source of national income being a main ingredient for tourism, also, as it contributes to solving the problem of unemployment. Predominantly, the lodging sector supports the balance of payments. At this place, a reading to "Alpha”;"Beta”;"Gamma”;"Delta”;and "Omicron”—Corona Variants reflects significant implications. On the one hand, there exists a challenge to Egypt's hotel industry following the pandemic attack;on the other hand, and by considering the case of relaxing the international restrictions, the international tourism is expected to recoup. Egypt has relatively benefited in the first half of 2021 when many Europeans escaped the lower temperature in winter in their homelands opting warm holiday destinations. The primary readings also expect the continuity in this increase. The macro-trend right here considers the shift in favor of a thoroughly managed risk with enhanced pliability, adopting a view of creating value, and increasing trust, while the micro-management considerations signify enhancing the sustainability of the sector performance by means of raising lodging hygienic attributes and approving innovative approaches. Luxury hotel, led by their executives, can significantly contribute and steer this trend mainly for cost tolerance estimates and for the potentiality of cost recovery. This study addresses the ways with which "Alpha”;"Beta”;"Gamma”;"Delta”;and "Omicron” Corona variants necessitate more sustained hotel management practices and helps to establish knowledge and techniques that assist the lodging sector in Egypt. A further goal of this study is to endorse the hotel managers' impact on counteracting the upshots of Variants' progressions. The study is multifaceted in "scale” and "scope,” since it is based on an investigation of the effects of large-scale public health emergencies in the lodging sector. A qualitative methodology is set via conducting online and offline surveys to examine how the pandemic affect lodging sector operations, and how far Egypt's luxury hotel managers tolerate both burdens of managing the emergency and creating sustained plans for recovery. Henceforward, the study constructs a frame for sustained lodging sector recovery. The paper's scientific value is that it functionalizes a broad inductive method of qualitative research in which a merge of the interpretation of management enabling factors and health enabling trends in the lodging sector and luxury hotel managers' responses obtained through exploratory qualitative research is utilized to cluster the managers' responses and thus generalize the information in the setting of a Framework for Health Crisis Management in the lodging sector. The Framework for Health Crisis Management also adds value as it amalgamates a combination of input factors of management and health enablers;a transformation via the change actions;an output of containing the effect of the pandemic through the enhanced managers' capabilities and hotels' health hygiene readiness;and an outcome implication of medium-term stabilizing effects that leads to an impact effect of sustained lodging sector recovery. This configures an input, transform (actions), output, outcome, and impact result chain. The study reaches the findings that sustainable recovery in the lodging sector—being sensitive to the uncertainty that the Virus "Variants” create—necessitates the merge between managing the emergency, adopting pliable approaches, alongside with the enhancement of the managers' (hoteliers) role as a supporting premise.

SPIKE-RECEPTOR BINDING DOMAIN (SRBD) ANTIBODIES SECRETION IN COVID 19 SURVIVORS AND NON-SURVIVORS POST-PRE-ENDEMIC VACCINATION

The development of a vaccine for SARS-COV-2 began in mid-2020 with the aim of stimulating an individual's immune response against SARS-CoV-2 infection. The purpose of this study was to determine the levels of post-vaccine SRBD antibody secreted in COVID-19 survivors and non-survivors. Antibodies are considered to play a more important role in evaluating immunity because antibody tests may provide information about a person's immune status against SARS-CoV-2. The study was conducted at Husada Utama Hospital, Surabaya, Indonesia, in April - May 2021. The samples were taken prospectively with a total sample of 60 patients, consisting of 40 non-survivors and 20 survivors of COVID-19 who had received Sinovac vaccine doses 1 and 2. Examination of Sars-CoV-2 SRBD antibody was conducted by using CL series of Mindray device by means of CLIA method. The average level of antibody was assessed in each sample group and the results were subjected to the Mann Whitney test. The mean SRBD antibody level in female patients was 428.24 ± 271.25, while in male patients it was 310.40 ± 113.71 U/mL. The results of the Mann Whitney test revealed a P-Value of 0.09 > 0.05, indicating no difference in post-vaccine SRBD antibody levels between females and males, but there were differences in SRBD antibody levels in COVID-19 survivors and non-survivors with a P-Value of <, i.e. 0.00 < 0.05 There was no difference in post-vaccine SRBD antibody levels between females and males in COVID-19 survivors and non-survivors, but there were differences in post-vaccine antibody levels between COVID-19 survivors and nonsurvivors. [ FROM AUTHOR] Copyright of Folia Medica Indonesiana (2355-8393) is the property of Universitas Airlangga and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

Towards Sustainable Living through Sentiment Analysis during Covid19

Artificial intelligence is the process of the machine to perform with the simulation of human intelligence. Computing within the field of emotions paves the recognitions to sentiment analysis. Sentiment analysis is the method of capturing the emotions behind a text whether or not it's positive, negative or neutral. Sentiment Analysis (SA) or Opinion Mining (OA) is the process to provide computational treatment to unstructured data to categorize and identify the sentiments or emotions expressed in a piece of text. It combines Natural Language Processing Techniques and Machine Learning Techniques. This technology is additionally referred to as opinion mining or feeling computing. Sentiment Analysis uses the ideas of machine learning alongside an AI based process called NLP to extract and analyse the data, emotions, information from the text. This work explores the impact of social media during covid 19 and possible link between sustainable living and health care with the usage of sentiments. This paper address the sustainable development goal 3 (good health and wellbeing) of SDG 2030 and a possible way towards sustainable living through sentiment analysis. © The Electrochemical Society

Fear of missing out during a pandemic: the driving factors of telemedicine application acceptance

COVID-19 pandemic changed how society behaves. Travel and social restrictions, commonly associated with the term lockdown became popular and ubiquitous. Given the rise of gig economy and mobile app delivery in the past several years, combined with lockdowns during the pandemic, and the application of telemedicine becomes essential. Halodoc is one of the popular telemedicine applications in Indonesia, having several useful features such as text-based doctor consultation and prescription drug order-delivery, and Halodoc is easily preferred by many. This article explored the motivation behind using Halodoc as the preferred method of getting health service during the pandemic, behind the perceived usefulness and perceived ease of use of the application, we found that fear of missing out (FOMO) has an indirect role in the application adoption in society, especially during lockdowns, where social interaction is limited to social media and other internet-based platforms. The reason why FOMO can be an important factor in technology adoption and how advertisers should explore FOMO is further discussed. © 2022, Institute of Advanced Engineering and Science. All rights reserved.

Global Health Strategies in the Face of the COVID-19 Pandemic and Other Unprecedented Threats.

Global health is evolving as a discipline aiming at exploring needs and offering equitable health services for all people. Over the past four decades, several global initiatives have been introduced to improve the accessibility of primary health care (PHC) and solve most health issues at this level. Historically, the 1978 Alma-Ata and 2018 Astana Declarations were perhaps the most important documents for a comprehensive approach to PHC services across the world. With the introduction of the United Nations Sustainable Development Goals in 2015, developments in all spheres of human life and multi-sectoral cooperation became the essential action targets that could contribute to improved health, well-being, and safety of all people. Other global initiatives such as the Riyadh Declaration on Digital Health and São Paulo Declaration on Planetary Health called to urgent action to employ advanced digital technologies, improve health data processing, and invest more in research management. All these initiatives are put to the test in the face of the coronavirus disease 2019 (COVID-19) pandemic and other unprecedented threats to humanity.

Survey data of determinants related to Covid-19 preventive behaviors during the second waves in Indonesia using the reasoned action approach.

The dataset presented in this article examines preventive behaviors related to Covid-19 among Indonesians, i.e., wearing a mask, hand washing, and distancing, and its related determinants. Data collection was carried out when Indonesia was facing the second waves due to the rapid transmission of the Delta variant virus. The data assessing socio-demographic information, beliefs related to Covid-19 preventive behaviors based on the reasoned action approach, general beliefs about Covid-19, and Covid-19 preventive behaviors, from 18th June to 18th August 2021, gathering a total of 863 completed responses. The sampling technique in this online survey used a combination of purposive and snowball sampling methods to gather the participants via social media such as Instagram, Twitter, Facebook, and WhatsApp throughout Indonesia. The survey data were analyzed using frequency distributions and bivariate correlation analysis. The data will help to understand the psychosocial determinants of Covid-19 preventive behaviors and provide insight for the development of behavior change intervention to limit the spread of Covid-19 among Indonesians.

The impact physical distancing during the COVID-19 pandemic on mental health among adolescents: a systematic literature review

The spread of the coronavirus disesase 2019 (COVID-19) virus is relatively fast and has infected hundreds of countries. The number of people suffering from COVID-19 continues to increase and is increasingly concerning. To reduce the possibility of spreading the Coronavirus, which is easily contagious, the World Health Organization (WHO) advises the public to maintain a safe distance from other people through physical distancing. This study is a systematic review using the preferred reporting item for systematic reviews and meta-analyzes (PRISMA) method using 454 articles from online journal databases. The databases used in the literature search were Pubmed, Science Direct, Sage, Emerald, and Proquest from 2020-2021. Based on the inclusion and exclusion characteristics, there were 8 of 454 articles met the inclusion criteria, and select for in-depth analysis. Physical distancing policy has an impact on adolescent mental health. Some of the mental disorders experienced by adolescents include feeling lonely, anxious, stressed, psychiatric disorders, to emotional disturbances. Boys have a higher increase in mental health problems than girls. We need a social network and social support specifically in adolescents to maintain physical distancing during the adolescent mental health policy in the COVID-19. © 2022, Intelektual Pustaka Media Utama. All rights reserved.

Challenges for Healthcare Workers Caring for COVID-19 Patients in Indonesia: A Qualitative Study.

COVID-19 pandemic raises various challenges faced by health workers in hospitals. This study explored strategies for overcoming challenges in caring for COVID-19 patients at hospitals in Indonesia based on healthcare workers' experience. In-depth interviews were employed with 28 healthcare workers (physicians and nurses) who were purposively sampled. Data were collected via phone and analysed using the Colaizzi method. Five following challenges were found: difficulties in working with personal protective equipment (PPE), offline training for handling Covid and using PPE not being implemented evenly for all health workers, physical and psychological fatigue, difficulties in carrying out health education and assessment towards patients and families, and limited resources to cope with the COVID-19 pandemic. Meanwhile, some barriers require support from the government, public and hospital managers. The information gained from research on the strategies for caring for COVID-19 patients can contribute to better preparedness for hospitals and health workers facing the COVID-19 pandemic.

Vitamin and mineral supplementation for ß-thalassemia during COVID-19 pandemic.

AIM: Low levels of immune-related micronutrients have been identified in ß-thalassemia samples. Moreover, the excess amount of iron, contributing to oxidative stress in the pathogenesis of the disease, alters the immune system in ß-thalassemia, which is important during the COVID-19 pandemic. MATERIALS & METHODS: Searches of PUBMED and EMBASE were conducted to identify the level and supplementation of micronutrients in ß-thalassemia, published from 2001-May 2020. RESULTS: The review found six observational and five interventional studies supporting the importance of supplementing vitamins and minerals among patients with ß-thalassemia. CONCLUSION: Supplementation of immune-related vitamins and minerals might bring benefits to the immune system, especially in reducing oxidative stress in ß-thalassemia.